Chorionic Gonadotrophin Veterinary Pharmacy Injection (HCG) Trade
Name Duoqingsu GMP
It occurs as the white freeze-dried blocks or powder.
Function and use
It is hormone drug and mainly used to make the follicle develop to
be mature continuously to induce ovulation. After ovulation , it
makes theca folliculi and granulose cells turn into luteal cells ,
and then promote the luteal cells to secrete progestational
hormone. For male animals , it can stimulate the development of
leydig cells , accelerate the secretion of androgen , boost the
growth and maturation of sexual organs and sub-sexual grands , and
promote testicular function and spermiogenesis.
It is commonly used to : 1 Treat follicular cysts
2 Promote estrus , maturation and ovulation.
3 Strengthen luteal action , prevent threatened abortion or
habitual abortion and postpartum breast milk insufficiency , etc.,
and serve for the early fetus protection.
4 Prevent and treat infertility caused by early luteal hypoplasia.
5 Treat male animals with symptoms such as poor sexual desire ,
excessive copulation , low semen volumes , poor sperm vitality and
cryptorchidism , etc.
6 Stimulate chicken , ducks , geese and other poultry to lay eggs,
reduce the break-in period for laying eggs or shorten the
broodiness period of poultry.
Usage and Dosage
When injected , it shall be diluted with sterile water for
injection or sterilized saline water.
Application in Cattle Reproduction
1. Estrus induction : 1000-1500 IU of PMSG shall be applied 25-30
days after delivery . Intramuscular injection of 1000-1500 IU of
HCG 12 hours after the estrus while conducting the first breeding
and mating again on the next morning can obtain a normal conception
rate and shorten the calving interval.
2. Synchronized ovulation: Injection of 1000-1500 IU of HCG within
48-72 hours after using 0.2mg of PG for synchronized treatment
while giving the first insemination can further promote ovulation
synchronization and enhance the conception rate after synchronized
3.Treatment of follicular cysts : intramuscular injection of
10000-2000IU of HCG can be used with 10-15mg of dexzmethasone ( it
shall not be applied in high productive dairy cows as it affects
milk yield) . If the drug is ineffective once , the dosing shall be
repeated once. The next estrus will be better for the mating.
Relapses of the disease shall be observed after the successful
treatment. Intramuscular injection of 2000IU of HCG shall be
implemented after estrus to prevent relapses.
4. Treatment of anestrus and delayed ovulation : intramuscular
injection of 1000-2000IU of HCG is given for anetrus catttle and
the dosing shall be repeated every 7-11 days: intramuscular
injection of 1000-2000IU of HCG is given for cattle with delayed
ovulation a few hours prior to breeding or during breeding.
5. Treating luteal hypoplasia , preventing early habitual abortion
and enhancing pregnancy rate in estrus:
intramuscular injection of 3000-5000 IU of HCG on the breeding day
or 4th-5th day after breeding can
significantly improve the pregnancy rate in estrus.
6. Treatment of low sexual desire for bulls : intramuscular
injection of 5000-100000 IU of HCG.
Application in Porcine Reproduction
1. Estrus and ovulation induction: Intramuscular injection of 400
IU of PMSG plus 200IU of HCG on the day of ablactation or the next
day , most sows can be made in heat 5-8 days after ablactation.
2. Control and acceleration of ovulation : Intramuscular injection
of 500-1000 IU of HCG during maling if estrus occurs after sows
being treated with Tongfasu (PMSG and HCG injection) and PMSG can
promote the synchronization of ovulation and improve pregnancy rate
and litter size.
3. Treatment of sow follicular cysts: intramuscular injection of
2000IU; once a day for 3-5 consecutive days.
4.Treatment of sow anoestrus: good effect can be achieved when sows
are given intramuscular injection of 2000 to 3000IU of HCG , once
in the morning and in the evening respectively for 2-3 consecutive
Obvious curative effect can be achieved when the said dosage are
used cooperatively with 1000-1500 IU of PMSG.
5. Intramuscular injection of 1000-5000 IU of HCG for 3-5
consecutive days for male pigs with poor sexual desire , low semen
quality , cryptorchidism and impotence.
Application in Other Domestic Animales
1. Synchronization of ovulation for sheep : Injection of 400 IU of
HCG within 48-72 hours after 0.2mg of PG, simultaneous insemination
can further promote the synchronization of ovulation and improve
the pregnancy rate after estrus synchronization.
2. Enhancing super-ovulation effects on sheep : intramuscular
injection of 500-2000 IU of HCG within 48-72 hours after treatment
for super-ovulation can promote follicle maturation and ovulation.
3. Promoting sexual desire and gonad development of male sheep:
intramuscular injection of 1500-2000 IU of HCG.
4. Intramuscular injection of 50-100IU of HCG can induce ovulation
for female rabbits without normal estrus and ovulation.
5. Intramuscular injection of 200-500IU of HCG for domestic fowls,
2 to 3 times a week.
1. Should be prepared as needed since it is easy to lose efficacy
in aqueous solution ; excess injection should be kept sealed and
stored in the temperature between 0℃ and 5℃
2. Contraindicated in food animals and only used for animal
3. Should not be touched by children