Western Medicine High Effective Oxytetracycline Capsules Bp 250mg
Original Gonorrhea and Syphilis Innovative Broad-Spect
Each capsule contains Oxytetracycline Hydrochloride equivalent to
250 mg Oxytetracycline.
Broad and medium spectrum antibiotics.
Oxytetracycline is a bacteriostatic antibiotic and inhibits
bacterial protein synthesis(30S ribosomes). In vitro activity does
not necessarily imply in vivo efficacy.
It is particularly effective in vitro against the following
Vibrio cholerae, Ureaplasma urealyticum, Mycoplasma pneumoniae,
Chlamydia trachomatis, Chlamydia psittaci, Borrelia burgdorferi,
penicillin - sensitive Neisseria gonorrhoeae and Rickettsiae;
Oxytetracycline is also effective against the following organisms
Clostridium tetani, Listeria monocytogenes, Haemophilus ducreyi,
Campylobacter jejuni, Leptospira, Actinomyecs israelii, Bacillus
anthracis, Pasteurella multocida, Streptobacillus moniliformis,
Infections caused by susceptible strains of pathogens:
Upper and lower respiratory tract: Sinusitis pharyngitis, pneumonia
and psittacosis Genito-urinary tract; Non-specific urethritis ,
Iymphogranuloma venereum , chancroid and granuloma inguinale ,
gonorrhoea, gonococcal salpingitis , epididymitis , acute
epididymo-orchitis , endocervical infections and syphillis ( in
cases of penicillin allergy).
Trachoma and indusion conjunctivitis; Intestinal:
Cholera, Whipple's disease, ana tropical sprue; Miscellaneous:
Rickettsial infections, brucellosis, tularemia, actinomycosis, Lyme
disease, yaws, relapsing fever,
Leptospirosis , during the early infective phase.
In patients with renal impairment.
Hypersensitivity to any tetracycline.
Oxytetracycline should not be given in pregnancy, lactation and in
Use with care in patients with liver function impairment;
Do not use concomitantly with hepatotoxic medicines;
Tooth discolouration , enamel hypoplasia and retarded bone growth
may occur in children under the age of 12 years. These effects may
also occur in the foetus if given to prenant women;
Symptoms of myasthenia may be aggravated;
Photosensitivity may occur (see " Side effects and Special
Pseudotumor cerebri may occur.
DOSAGE AND DIRECTIONS FOR USE:
Oxytetracycline should be taken either one hour before meals or two
hours after meals. The maximum dose for oxytetracyline should not
exceed 3g daily for adults and 50mg/kg bodymass/day for children.
The usual dose for oxytetracycline for the commonly occurring
infection , depending on the severity is 250 to 500 mg every six
For acne , the adult dosage is as follows: 250mg twice daily
SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Oxytetracycline is not indicated for treating commonly occurring
infections in children under 12 years of age.
Gastro-intestinal: Nausea, Vomiting , Diarrhea , Glossitis ,
Dysphagia related to oesophagitis.
Secondary fungal overgrowth (Candida Albicans): Oral candidiasis,
Vulvovaginitis, pruritus ani
Secondary bacterial overgrowth infections may occur.
Resisitant coliform organisms such as Proteus spp. may cause
Supper-infection due to resistant staphylococci may cause
Increased severity of uraemia and hepatotoxicity in patient with
renal disease given high doses.
Blood abnormalities: Haemolytic anaemia, Eosinophilia, Neutropenia,
Vitamin deficiencies may occur.
Allergic (hypersensitivity) reactions : Urticaria, Maculopapular
& Erythematous rashes, Exfoliative dermatitis, Exacerbation of
systemic lupus erythematosus pericarditis , henoch-Schonlein
purpura (anaphylactoid purpura) , Angioneurotic oedema ,
Photosensitivity of the skin and nails; onycholysis and nail
discolouration may occur.
The use of expired oxytetracycline may lead to the Fanconi-type
syndrome which is characterised by polyuria and polydipsia with
nausea , vomiting , proteinuria, glucosuria, acidosis and
Raised intracranial pressure ( pseudotumor cerebri).
Absorption of oxytetracycline is diminished by milk , alkalis ,
aluminium hydroxide and other and trivalent caution such as calcium
iron and magnesium if they are give concomitantly.
Doses of anticoagulants may need to be reduced if given
concomitantly with oxytetracycline.
Penicillin should not be given concomitantly with oxytetracycline
as antagonism in action may occur.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
See "side effects and special precautions". Treatment is
symptomatic and supportive.
A hard gelatin capsule (Size 0) with dark green cap and light green
Store in a cool dry place away from light.
KEEP OUT OF REACH OF CHILDREN.