ISO certified Tilmicosin base/tilmicosin phosphate CAS
number:0108050-54-0 USP34 DMF 20KG/Drum Antibacterial/Macrolide
Tilmicosin is a macrolide antibiotic. It is used in veterinary
medicine for the treatment of bovine respiratory disease and bovine
respiratory disease associated with Mannheimia (Pasteurella)
Tilmicosin phosphate is a salt of the semi-synthetic antibiotic
derivative of desmycosin (tylosin B), a minor co-metabolite of
tylosin, prepared by mixing the active tilmicosin with phosphoric
acid to provide improved solubility and enhanced pharmacokinetics.
Tilmicosin is a broad sepctrum antibiotic, providing good
protection against Pasteurella in livestock.
Tilmicosin is absorbed orally and subcutaneously, but not
completely. The apparent distribution volume was high and the drug
concentration in lung tissue was high. With good tissue
penetration, can quickly and completely from the blood into the
breast, milk drug concentration is high, maintaining a long time,
the half-life of milk up to 1--2 days.
Inhibition of gram positive bacteria and some gram negative
bacteria, mycoplasma, spirochetes have antibacterial activity; has
stronger than tylosin on Actinobacillus pleuropneumoniae,
Tilmicosin is not static, once a cow can be killed by intravenous
injection of 5mg/kg, pigs, horses and primates are also easy to
death, the toxic effect of the target organ is the heart, can cause
negative effects on the heart.
Mainly used for preventing and treating livestock pneumonia (by
Actinobacillus pleuropneumoniae, Pasteurella, mycoplasma
infection), avian mycoplasma disease and lactation mastitis animal.