Sign In | Join Free | My
Wuhan uni-pharma bio-tech co.,ltd
Wuhan Uni-pharma Bio-tech Co.,Ltd
Home > Veterinary Pharmaceuticals >

Pale Yellow Powder Veterinary Pharmaceuticals Valnemulin Hydrochloride Bacteriostatic Agent

Wuhan uni-pharma bio-tech co.,ltd
Wuhan uni-pharma bio-tech co.,ltd
Province/State: Hubei
Country/Region: China
Tel: 86-27-82316816

Pale Yellow Powder Veterinary Pharmaceuticals Valnemulin Hydrochloride Bacteriostatic Agent

MOQ : 500 Kilograms
Price : USD1.00-20.00
Payment Terms : L/C, D/A, D/P, T/T, Western Union, MoneyGram, MoneyGram
Supply Ability : 50 Metric Ton/Metric Tons per month
Delivery Time : 20 days
Brand Name : Unipharma
Certification : EU-GMP,ISO9001,COS,GSP
Place of Origin : CHINA
Packaging Details : 20 KG/drum or 10kg/drum
Empirical Formula (Hill Notation) : C31H52N2O5S · HCl
Molecular Weight : 601.28
CAS Number : 133868-46-9
format : neat
application(s) : HPLC: suitable,gas chromatography (GC): suitable
storage temperature : -20°C
Contact Now

ISO certified Valnemulin hydrochloride CAS:133868-46-9 Broad-spectrum bacteriostatic agent for veterinary use


Valnemulin is a new generation of pleuromutilin (pleuromutilin) class of semi synthetic antibiotics, two terpenes, and tiamulin belong to the same class of drugs and antibiotics is a special animal. It is mainly used for the prevention of Mycoplasma and gram positive bacteria infection in pigs, cattle, sheep and poultry. Approved by the European Community in 1999 for the prevention and treatment of swine dysentery caused by short hyodysenteriae (Brachyspira) infection caused by swine dysentery and Mycoplasma pneumoniae infection caused by local pneumonia in pigs. It was the first European approved veterinary drug premix and was listed as a veterinary prescription. January 2004 was approved by the prevention of colon bacteria having short helix (Brachyspira pilosicoli) infection in pig colon caused by leptospirosis (colitis, diarrhea and colitis) in a mild form of growing pigs by intracellular bacteria infection caused by porcine proliferative enteropathy (ileitis ileitis). B.hyodysenteriae, having short colon bacteria leptospira and intracellular bacteria is most arch-criminal enteritis in growing pigs.


valnemulin is inhibiting bacterial protein synthesis at the ribosome synthesis level, high concentration also inhibited RNA. Mainly antibacterial, but also sterilization at high concentrations. The antibacterial spectrum is wide, and it is effective for G+ and G- bacteria, and is highly effective to the genus and Leptospira, but it has low effect on the intestinal bacteria such as E. coli and Salmonella.


Pig oral valnemulin rapid absorption, absorption rate of more than 90% hours after administration of 1-4 reached the highest concentration of plasma, plasma half-life of 1.3-2.7 hours. A single oral dose of 10 mg/kg body weight of valnemulin hydrochloride, the peak time of 1.85 hours, the peak concentration of 1.29 g/ml, the area under the curve (AUC) of 5.58 g/ml/ hours. When the dose of 25mg/kg body weight, the peak time of 2.9 hours, the peak concentration of 2.67 g/ml, the area under the curve (AUC) of 18.23 g/ml/ hours; when the dose of 50mg/kg body weight, the peak time of 4.15 hours, the peak concentration of 6.23 g/ml, the area under the curve (AUC) of 67.3 g/ml/ hours; plasma the concentration and dosage of linear relationship. After repeated administration, a slight accumulation occurred, but within 5 hours. 2 times a day, the weight of the 5 mg/kg was repeated and the plasma concentration remained stable for a period of 7.5 days. Because of the obvious first pass effect, the plasma concentration was affected by the administration method. But the valnemulin mainly concentrated in tissues, especially in lung and liver tissues. 5 days 15 doses of radioactive markers of valnemulin last 1 to pig, liver concentration is 6 times greater than the plasma concentration. 15mg/kg weight per day, 2 times a day to feed, fed for 4 weeks, after stopping the drug for 2 hours, the liver concentration of 1.58ug/g, lung concentration of 0.23ug/g, while the plasma concentration is lower than the detection value.

Valnemulin 200ppm mixed feeding, the drug concentration of colon contents for 5.20ug/ml; 75ppm mixed feeding, the contents of the colon drug concentration is 1.68ug/ml. There was a linear relationship between the concentration of colonic contents and the concentration of mixed feed.

Valnemulin of metabolism and excretion of metabolites widely in swine, mainly by the rapid excretion of bile and feces, radioactive marker 87% 1 in the last administration within 3 days after discharge, excretion accounted for about 3% of the same period in urine.


Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Certificate of analysis

PRODUCT NAME:Valnemulin hydrochlorideBATCH NO:S70713
MFG .DATE06/2016EXP .DATE05/2019
SAMPLING DATE07/07/2016REPORT DATE14/07/2016
TesI itemsSpecificationsResults
CharacteristicPale yellow non crystalline powderComplies
Acidity PH3.0-6.04.3
Specific rotation+15.5- 18.0+16.4
Moisture content≤4.0%1.40%
Related substance≤3.0%1.60%
Assay:96.0% ~ 102.0%97.80%
C31H52N2O5S · HCl

Product Tags:

veterinary medicine


medicine for animals

China Customized Inflatable Bumper Ball Game Bubble Adult Grass CE supplier

Pale Yellow Powder Veterinary Pharmaceuticals Valnemulin Hydrochloride Bacteriostatic Agent Images

Inquiry Cart 0
Send your message to this supplier
Enter your email please.
To: Wuhan uni-pharma bio-tech co.,ltd
Characters Remaining: (0/3000)
Inquiry Cart 0