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Milky White Liquid Intravenous Fat Emulsion Infusion Medicine 10% / 250ml Fat Emulsion Injection / Solution

Wuhan uni-pharma bio-tech co.,ltd
Wuhan uni-pharma bio-tech co.,ltd
Province/State: Hubei
Country/Region: China
Tel: 86-27-82316816

Milky White Liquid Intravenous Fat Emulsion Infusion Medicine 10% / 250ml Fat Emulsion Injection / Solution

Brand Name : Unipocithin 10%
Model Number : 10% 250ml
Certification : GMP ,ISO
Place of Origin : CHINA
MOQ : 30000 bottle
Price : USD2.3-USD2.5/Bottle
Payment Terms : L/C, D/A, D/P, T/T, Western Union
Supply Ability : 500000 bottles/Month
Delivery Time : 40 Days
Packaging Details : one bottle/box,9 bottles/middle boxs ,12 middle boxs/carton
Specifcation : 10%/250ml
Characteristics : milky white liquid
Compostion : soybean oil 25g, egg lecithin 3g and glycerol 5.5g and and Water for Injection q.s
Function : provide calories,energy, certain nutrient (essential fatty acids)
Admistration : intravenous
Use : Sterile & Nonpyrogenic
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Fat Emulsion 10% 250ml soybean oil, egg lecithin and glycerol provide calories,energy,certain nutrient


10% Intravenous Fat Emulsion is a sterile, non-pyrogenic fat emulsion prepared for intravenous administration as a source of calories and essential fatty acids. It is made up of 10% Soybean Oil, 1.2% Egg Yolk Phospholipids, 2.25% Glycerin, and Water for Injection. In addition, sodium hydroxide has been added to adjust the pH so that the final product pH is 8. pH range is 6 to 8.9.

The soybean oil is a refined natural product consisting of a mixture of neutral triglycerides of predominantly unsaturated fatty acids with the following structure:

where , and are saturated and unsaturated fatty acid residues.

The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic (7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids have the following chemical and structural formulas:

Purified egg phosphatides are a mixture of naturally occurring phospholipids which are isolated from the egg yolk. These phospholipids have the following general structure:

and contain saturated and unsaturated fatty acids that abound in neutral fats. R3 is primarily either the choline or ethanolamine ester of phosphoric acid.


Glycerin is chemically designated C3H8O3 and is a clear colorless, hygroscopic syrupy liquid. It has the following structural formula:

10% Intravenous Fat Emulsion has an osmolality of approximately 300 mOsmol/kg water (which represents 260 mOsmol/liter of emulsion) and contains emulsified fat particles of approximately 0.5 micron size.

The total caloric value, including fat, phospholipid and glycerin, is 1.1 kcal per mL of Intralipid 10%. The phospholipids present contribute 47 milligrams or approximately 1.5 mmol of phosphorus per 100 mL, of the emulsion.


10% Intravenous Fat Emulsion is metabolized and utilized as a source of energy causing an increase in heat production, decrease in respiratory quotient and increase in oxygen consumption. The infused fat particles are cleared from the blood stream in a manner thought to be comparable to the clearing of chylomicrons.

10% Intravenous Fat Emulsion will prevent the biochemical lesions of essential fatty acid deficiency (EFAD), and correct the clinical manifestations of the EFAD syndrome.


10% Intravenous Fat Emulsion is indicated as a source of calories and essential fatty acids for patients requiring parenteral nutrition for extended periods of time (usually for more than 5 days) and as a source of essential fatty acids for prevention of EFAD.


The administration of 10% Intravenous Fat Emulsion is contraindicated in patients with disturbances of normal fat metabolism such as pathologic hyperlipemia, lipoid nephrosis or acute pancreatitis if accompanied by hyperlipidemia.


Caution should be exercised in administering

10% Intravenous Fat Emulsion to patients with severe liver damage, pulmonary disease, anemia or blood coagulation disorders, or when there is danger of fat embolism.


This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum.

Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.


When 10% Intravenous Fat Emulsion is administered, the patients capacity to eliminate the infused fat from the circulation must be monitored by use of an appropriate laboratory determination of serum triglycerides. Overdosage must be avoided.

During long term intravenous nutrition with Intralipid® 10%, liver function tests should be performed. If these tests indicate that liver function is impaired, the therapy should be withdrawn.

Frequent (some advise daily) platelet counts should be done in neonatal patients receiving parenteral nutrition with 10% Intravenous Fat Emulsion .

Drug product contains no more than 25 mcg/L of aluminum.

Carcinogenesis, Mutagenesis, Impairment of Fertility:

Studies with Intralipid® have not been performed to evaluate carcinogenic potential, mutagenic potential, or effects on fertility.

Pregnancy Category C:

Animal reproduction studies have not been conducted with Intralipid®. It is also not known whether 10% Intravenous Fat Emulsion can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. 10% Intravenous Fat Emulsion should be given to a pregnant woman only if clearly needed.

Nursing Mothers:

Caution should be exercised when 10% Intravenous Fat Emulsion is administered to a nursing woman.




The adverse reactions observed can be separated into two classes:

  1. Those more frequently encountered are due: either to contamination of the intravenous catheter and result in sepsis, or to vein irritation by concurrently infused hypertonic solutions and may result in thrombophlebitis. These adverse reactions are inseparable from the hyper-alimentation procedure with or without 10% I.V. Fat Emulsion.
  2. Less frequent reactions more directly related to 10% Intravenous Fat Emulsion are: a) immediate or early adverse reactions, each of which has been reported to occur in clinical trials, in an incidence of less than 1 %; dyspnea, cyanosis, allergic reactions, hyperlipemia, hypercoagulability, nausea, vomiting, headache, flush-ing, increase in temperature, sweating, sleepiness, pain in the chest and back, slight pressure over the eyes, dizziness, and irritation at the site of infusion, and, rarely, thrombocytopenia in neonates; b) delayed adverse reactions such as hepatomegaly, jaundice due to central lobular cholestasis, splenomegaly, thrombocytopenia, leukopenia, transient increases in liver function tests, and overloading syndrome (focal seizures, fever, leukocytosis, hepatomegaly, splenomegaly and shock).

The deposition of a brown pigmentation in the reticuloendothelial system, the so-called ” intravenous fat pigment,” has been reported in patients infused with 10% Intravenous Fat Emulsion . The causes and significance of this phenomenon are unknown.


In the event of fat overload during therapy, stop the infusion of 10% Intravenous Fat Emulsion until visual inspection of the plasma, determination of triglyceride concentrations, or measurement of plasma light-scattering activity by nephelometry indicates the lipid has cleared. Re-evaluate the patient and institute appropriate corrective measures. See WARNINGS and PRECAUTIONS.

Principal Display Panel - Bag Label

10% I.V. Fat Emulsion

For Intravenous Use

Each 100 mL contains:

Soybean Oil 10.0 g

Phospholipids (from powdered egg yolk) 1.2 g

Glycerin, USP 2.25 g

Water for Injection q.s.

Calories 110 kcal

pH 8.0 (6.0-8.9) adjusted with sodium hydroxide.

Use only if bag and seal are undamaged. Administer intravenously.

Do not add medications to this emulsion. Contains no more than 25 μg/L of aluminum.

Sterile-Nonpyrogenic. See Directions Before Using. Single Dose Container. Do not store
above 25
°C (77°F). Do not freeze 10% Intravenous Fat Emulsion ; If accidentally frozen, discard the bag.

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infusion drugs


infusion injection

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