Western Medicine (DAZECLOX) BP AMPICILLIN + CLOXACILLUIN POWDER FOR
IJNECTION 250mg + 250mg (For I.M. Use)
Ampicillin + Cloxacillin Sterile Powder for Injection BP.
This powder is made up into a solution for injection.
Each vial contains:
Ampicillin (as sodium) BP 250mg
Cloxacillin (as sodium) BP 250mg
Infections cause by susceptible organisms where a mixed infection
is present and includes penicillin-resistant staphyococci. Useful
in the treatment of respiratory tract infection,ear,nose and throat
infections,urinary tract infections,gastro-intestinal
infections,skin and soft tissue infections, pelvic
adiministration-this must not be used in the eye either
sub-conjunctivally for locally.
Before initating therapy careful inquiry should be made concerning
previous hypersensitivity reactions to beta-lactams. Anaphylactic
shock may occur. Adrenaline or corticosteroids amd anti-histamines
should be used to treat anaphylaxis.
Dosage should be adjusted in patients with renal impairment.
As with other penicillin drugs,side effects are usually of a mild
and transitory nature. They may include
nausea,diarrhea,indigestion,or occasionally rash,either
urticarial,which suggests penicillin hypersensitivity,or
erythematous. Any erythematous rash may occur in patients with
glandular fever. In either case it is advisable to discontinue
therap. As with other beta-lactam antibiotics,anaphylaxis and other
hypersensitivity reactions (including interstitial nephritis) have
been reported rarely. Bollous reactions have been reported very
rarely. Other side-effects include hepatitis,cholestasis induced
jaundice or the transient increase in transaminases.
Ampicillin/Cloxasillin may decrease the effcacy of oestrogen
containing oral contraceptives.
There are no konwn symptoms of overdosage.
See side effects and special precautions.
Treatment is symptomatic and supportive.
|Adults and children over 10 years:||500mg-1g|
|For I.M. Use every 4-6 hours or as dicated by the severity of the
|Children 2-10years:||250mg-500mg every 4-6 hours|
|Neonates:||75mg (i.e. neonatal vial) every 8 hours|
Children and neonates dosages should
correspond to a daily dosage of 50-150mg/kg
|Note:Patient with renal insufficiency may require a reduced dosage.|
Ass 1.5ml of water for injection BP and shake vigorously till
powder is completely dissolved.
The solution must be used immediately.
Ampicillin/Cloxacillin injectable is compatible with commonly used
Ampicillin/Cloxacillin should not be added to infusion bottles
containing Dextran 40 injection its 5% dextroses. Cloxacillin has
been reported to be incompatible with aminoglycosides, teracyclines
and other antimicrobial agents including erythomycin and polymyxin
B sulphate. Should not be mixed with blood prodcuts or other
Store below 25°C in a dry place. Protect from heat and light.
Strictly to be dispensed by doctor's prescription.
Keep away from the reach of children.
10vials in a box
50vials in a box